Placebos are widely used in medical practice, although the exact numbers are not known. Surveys have shown that somewhere between 57-97% of doctors admit to using placebos in their clinical practice. Placebos would not be used so prevalently if they did not have positive effects, but it's vitally important that placebos are used as ethically as possible to avoid harming the doctor-patient relationship. Here, we outline different types of placebo usage, the ethical considerations and the current medical guidelines for placebos in clinical practice.